Anaphylaxis is triggered when you come in contact with an allergen through skin contact, stings, swallowing, or breathing in fine particles. Many types of food have been identified as causing severe allergic reactions in sensitive individuals. Even eating a very small amount of a problem food may cause a reaction in some people. In rare cases, exercising within a few hours after eating a specific food may cause an anaphylactic reaction. Some examples of common anaphylaxis triggers include peanuts, fish, milk, eggs, insect stings, and latex products.
Some people may have severe allergic reactions to certain types of medications, including penicillin, muscle relaxants, or aspirin. Inform all doctors, dentists, and pharmacists of any medication allergies you may have. Do not allow family, friends, or school personnel to give your child medication without your permission.
It's important to know what causes your severe reactions. If you are unsure, your doctor may run special tests to help identify your specific triggers.
IMPORTANT SAFETY INFORMATION ABOUT TWINJECT: Twinject is indicated in the emergency treatment of severe allergic reaction (type I) including anaphylaxis to stinging insects and biting insects, allergen immunotherapy, foods, drugs, diagnostic testing substances, and other allergens, as well as anaphylaxis to unknown substance or exercise-induced anaphylaxis.
Since the dose of epinephrine delivered from Twinject 0.15 mg is fixed at 0.15 mg, the physician should consider other forms of injectable epinephrine if doses lower than 0.15 mg are felt to be necessary (eg, patients who weigh less than 15 kilograms [approximately 33 pounds]).
Twinject should only be injected into the anterolateral aspect of the thigh. Accidental injection into the hands or feet may result in loss of blood flow to the affected area and should be avoided. DO NOT INJECT INTO BUTTOCK. DO NOT INJECT INTRAVENOUSLY.
Epinephrine should be administered with caution to patients with cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In patients with coronary insufficiency or ischemic heart disease, epinephrine may precipitate or aggravate angina pectoris as well as produce ventricular arrhythmias. It should be recognized that the presence of these conditions is not a contraindication to epinephrine administration in an acute life-threatening situation. Adverse reactions to epinephrine include transient, moderate anxiety; apprehensiveness; restlessness; tremor; weakness; dizziness; sweating; palpitations; pallor; nausea and vomiting; headache; and/or respiratory difficulties.
Twinject is designed as an emergency supportive therapy only and is not a replacement or substitute for immediate medical care.
