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Terms of Use

The information provided on our web site is intended for general informational and educational purposes. You should read and review these Terms of Use before accessing or using this web site. By accessing or using this site, you acknowledge that you have read, understood and agreed to the Terms of Use Agreement. These Terms of Use are by and between Shionogi Inc. (“Shionogi Inc.”) and you, someone who uses or accesses one of our Web sites. When we refer to ourselves as "we" or "Shionogi Inc." we mean our entire company, including any company that we control (for example, a subsidiary that we own).

  • As-Is Presentation. Shionogi Inc. makes no warranty or representation of any kind as to the information or materials on our web site. Access to and use of our web site and the content thereof is at your own risk. To the maximum extent permitted by law, Shionogi Inc. disclaims any and all warranties, express or implied, including warranties of merchantability, title, and fitness for a particular purpose. Neither Shionogi Inc. nor any party involved in creating, producing, hosting or delivering this web site or its contents shall be liable for any damages, including without limitation: direct, incidental, consequential, indirect, or punitive damages arising out of access to, use of or inability to use the web site, or any errors or omissions in the content thereof. This limitation includes damages arising from any viruses or other harmful code that may infect your computer equipment or from malicious persons who may make unauthorized use of the web site or its contents.
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  • Use of Ideas You Communicate. In the event and to the extent that you have any right, title, or interest in any intellectual property contained in any communication to us, including (without limitation) moral rights, you hereby grant to Shionogi Inc. a worldwide, non-exclusive, transferable, royalty-free, fully paid-up license to use, execute, perform, display, reproduce, modify, distribute, sell, have sold, make, have made, import, export, and create derivative works that Shionogi Inc. will own, and to authorize others to do any of the same, for whatever purpose that Shionogi Inc. may choose and under all rights, title, and interest that you have, including (without limitation) all intellectual property and moral rights.
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  • Void Where Prohibited. This web site and its contents are intended to comply with the laws and regulations in the United States. While available outside the United States, the content of this web site as it pertains to pharmaceutical products is intended for use only by residents of the United States. The laws and regulations of other countries may be different. Any offer for any product or service made on our web site is void where prohibited by law.
  • User Responsibility. By using any of our web sites, you agree to indemnify, defend and hold harmless Shionogi Inc., its officers, directors, employees, agents, suppliers, and third party affiliates from and against any and all losses, expenses, damages, and costs, including reasonable attorneys' fee, resulting from any violation by you of these Terms of Use.
  • Governing Laws. These Terms of Use and your use of the web site shall be governed by the laws of the United States of America and the State of Georgia without regard to conflict of law principles. By using this web site you agree that any legal action shall be brought exclusively in a federal or state court of competent jurisdiction sitting in the U.S. state of Georgia. If any provision of these Terms of Use is held to be unlawful, void or unenforceable, then such provision shall be severable without affecting the enforceability of all remaining provisions.

Please contact us with your questions about this privacy statement or about Shionogi Inc.'s handling of your information at:

regulatoryaffairs@shionogi.com

Copyright 2006, Shionogi Inc.
Last Modified:

INDICATION:

Twinject (epinephrine injection, USP 1:1000) is indicated in the emergency treatment of severe allergic reactions (Type I) including anaphylaxis to stinging insects (e.g. order Hymenoptera, which includes bees, wasps, hornets, yellow jackets and fire ants), and biting insects (e.g. triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g. radiocontrast media), and other allergens, as well as anaphylaxis to unknown substancess (idiopathic anaphylaxis) or exercise-induced anaphylaxis.

IMPORTANT SAFETY INFORMATION ABOUT TWINJECT:

Twinject should only be injected into the anterolateral aspect of the thigh. Accidental injection into the hands or feet may result in loss of blood flow to the affected area and should be avoided. DO NOT INJECT INTO BUTTOCK. DO NOT INJECT INTRAVENOUSLY.

Epinephrine should be administered with caution to patients with cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In patients with coronary insufficiency or ischemic heart disease, epinephrine may precipitate or aggravate angina pectoris as well as produce ventricular arrhythmias. It should be recognized that the presence of these conditions is not a contraindication to epinephrine administration in an acute life-threatening situation.

Adverse reactions to epinephrine may include flushing; apprehension; syncope; tachycardia; thready pulse with a fall in blood pressure; convulsions; respiratory difficulties; vomiting, diarrhea or cramps; pruritus; or angioderma. Twinject is designed as an emergency supportive therapy only and is not a replacement or substitute for immediate medical care.

Since the doses of epinephrine delivered from Twinject are fixed, the physician should consider other forms of injectable epinephrine if doses lower than those available from Twinject are felt to be necessary (e.g., patients who weigh less than 15 kilograms approximately 33 pounds). IN ALL CASES, THE PHYSICIAN SHOULD INSTRUCT THE PATIENT AND/OR ANY OTHER PERSON WHO MIGHT BE IN A POSITION TO ADMINISTER THE EPINEPHRINE, IN THE PROPER USE OF TWINJECT.

Please see complete prescribing information for more details.

Your doctor can give you more information about Twinject or call 1-800-849-9707. Ask your doctor if Twinject may be right for you.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

MedicAlert® is a Federally Registered Trademark and Service Mark.
MedicAlert and Kid Smart are registered trademarks and service marks of their respective owners.

Twinject is a registered trademark of Shionogi Inc.
© 2011 Shionogi Inc. Florham Park, NJ. All rights reserved. TWI.07.08.036.03

This web site and its contents are intended for use only by residents of the United States. Products discussed may have different labeling, regulatory requirements, and/or medical practices in other countries that may require reference to different or additional information.

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